Foxg1-Cre
品系全名
C57BL/6Smoc-Foxg1em1(Cre-WPRE-polyA)Smoc
目錄號
NM-KI-200156
品系狀態(tài) 活體
基因信息
基因名
Foxg1
品系描述
驗證數(shù)據(jù)
Fig 1. Cre-mediated recombination in brain of Foxg1Cre/+; Rosa26tdTomato/+?mice.
Fig 2. Detection of tdTomato (red) in various tissues of Foxg1Cre/+; Rosa26tdTomato/+?mice.?Expression tissues include: brain, retina, heart, lung, liver, stomach, salivary glands, brown fat, kidney, pancreas, small intestine, large intestine, ovary, thymus, adrenal gland. A few cells expressed in spinal cord, spleen, muscle, skin. (9-week old, female) (For more detailed information please contact our technical advisor.)?
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Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質(zhì)內(nèi)處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產(chǎn)物4-OHT(雌激素類似物)與ERT結合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。
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