Muc2-2A-CreERT2-IRES-tdTomato

品系全名

C57BL/6Smoc-Muc2em1(2A-CreERT2-tdTomato-Wpre-pA)Smoc

目錄號

NM-KI-200301

品系狀態(tài)

精子凍存

導出PDF

基因信息

基因名
Muc2

基因曾用名

MCM; wnn; 2010015E03Rik

染色體位置

7

NCBI ID

MGI ID

Ensembl ID

Pubmed

品系描述

將2A-CreERT2-tdTomato-Wpre-pA插入到小鼠Muc2基因終止密碼子處。

驗證數(shù)據(jù)

image.png

Fig 1. Active tdTomato expression was observed in the large intestine of Muc2CreERT2-IRES-tdTomato/+? mouse. WT, wild type as control.

image.png

Fig 2.?Active tdTomato expression was observed? in the small intestine of Muc2CreERT2-IRES-tdTomato/+?mouse. WT, wild type as control.

image.png

Fig 3.?No obvious tdTomato signal was observed in the stomach of Muc2CreERT2-IRES-tdTomato/+ mouse. WT, wild type as control.

image.png

Fig 4. Active tdTomato signal was observed in the colon of Muc2CreERT2-IRES-tdTomato/+?mouse. WT, wild type as control.

image.png

Fig 5. Active tdTomato signal was observed in the?cecum of?Muc2CreERT2-IRES-tdTomato/+?mouse. WT, wild type as control.

image.png

Fig 6.?TdTomato signal was observed in the small intestine of?Muc2CreERT2-IRES-tdTomato/+?mouse.WT, wild type as control.


image.png

Fig 7.?No obvious tdTomato signal was observed in the stomach of Muc2CreERT2-IRES-tdTomato/+?mouse. WT, wild type as control.

你也可能感興趣

Tamoxifen誘導Cre-ERT2小鼠 使用指南

Cre-ERT2在無Tamoxifen誘導的情況下，在細胞質內處于無活性狀態(tài)；當Tamoxifen誘導后，Tamoxifen的代謝產(chǎn)物4-OHT（雌激素類似物）與ERT結合，可使Cre-ERT2進核發(fā)揮Cre重組酶活性。

查看
【小鼠大學問】基因工程小鼠的命名規(guī)則

常見的基因工程小鼠可以分為兩種命名方式，包括基因定點修飾的小鼠命名，比如：敲除、敲入、點突變等等，和隨機轉基因的小鼠命名。

查看