hCD93

品系全名

C57BL/6Smoc-Cd93em1(hCD93)Smoc

目錄號

NM-HU-215065

品系狀態(tài)

胚胎凍存

導(dǎo)出PDF

基因信息

基因名
Cd93

品系描述

利用同源重組,將小鼠Cd93基因進行人源化修飾。

驗證數(shù)據(jù)

image.png

Fig1. Detection of CD93 expression in lung by RT-PCR.?Wild type: only one band at 273 bp with primers F1/R1(mCd93);Heterozygous: one band at 273 bp with primers F1/R1(mCd93) and one band at 129 bp with primers F2/R2(hCD93); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2.?Detection of hCD93 expression on endothelial cells in lung in hCD93 KI mice.

image.png

Fig3.?Detection of hCD93 expression on macrophages, monocytes and neutrophils in blood in hCD93 KI mice.

image.png

Fig4.?Detection of hCD93 expression on macrophages, monocytes and neutrophils in spleen in hCD93 KI mice.

image.png

Fig5.?Detection of hCD93 expression on macrophages, monocytes and neutrophils in bone morrow in hCD93 KI mice.


你也可能感興趣

Tamoxifen誘導(dǎo)Cre-ERT2小鼠 使用指南

Cre-ERT2在無Tamoxifen誘導(dǎo)的情況下,在細胞質(zhì)內(nèi)處于無活性狀態(tài);當Tamoxifen誘導(dǎo)后,Tamoxifen的代謝產(chǎn)物4-OHT(雌激素類似物)與ERT結(jié)合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。

查看
【小鼠大學(xué)問】基因工程小鼠的命名規(guī)則

常見的基因工程小鼠可以分為兩種命名方式,包括基因定點修飾的小鼠命名,比如:敲除、敲入、點突變等等,和隨機轉(zhuǎn)基因的小鼠命名。

查看