hTIM3
品系全名
C57BL/6Smoc-Havcr2em1(hHAVCR2)/Smoc
目錄號
NM-HU-00054
品系狀態(tài) 活體
基因信息
基因名
Havcr2
品系描述
通過同源重組，將小鼠Tim3基因進行人源化修飾。
應用領域：免疫治療；腫瘤研究；藥物篩選
*使用本品系發(fā)表的文獻需注明: hTIM3 mice (Cat. NO. NM-HU-00054) were purchased from Shanghai Model Organisms Center, Inc..
驗證數(shù)據(jù)
Fig1. Detection of TIM3 expression by PCR.?
Wild type: only one band at 248 bp with primers F2/R2(mTim3);
Homozygous: only one band at 328 bp with primers F1/R1(hTIM3);?
Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
?Fig2. Analysis of?hTIM3 expression on stimulated CD4+ and CD8+? T cells in hTIM-3 knockin mice by FACS.?(Completed in cooperation with?CrownBio)
Fig3. Analysis of hTIM3 expression at very low levels on naive T cells by FACS.
Fig4. Analysis of hTIM3 expression at high levels on CD11b+ myeloid cells by FACS.
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