Cx3cr1-Cre

品系全名

C57BL/6Smoc-Cx3cr1em1(iCre)Smoc

目錄號

NM-KI-200079

品系狀態(tài)

活體

導(dǎo)出PDF

基因信息

基因名
Cx3cr1

基因曾用名

-

NCBI ID

MGI ID

Ensembl ID

Pubmed

人類同源基因

CX3CR1

品系描述

利用CRISPR基因編輯技術(shù)，將iCre替換小鼠Cx3cr1基因的編碼區(qū)。
應(yīng)用領(lǐng)域：Cre工具鼠,單核吞噬細(xì)胞系統(tǒng)

驗(yàn)證數(shù)據(jù)

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Fig. 1 Cre-mediated recombination in the lung of Cx3cr1Cre/+; Rosa26tdTomato/+?mouse. TdTomato(red) expression can be detected in the pulmonary macrophage of Cx3cr1Cre/+; Rosa26tdTomato/+?mouse.

image.png

Fig. 2 Cre-mediated recombination in the liver of Cx3cr1Cre/+; Rosa26tdTomato/+?mouse. TdTomato(red) expression can be detected in the hepatic kupffer cells? of Cx3cr1Cre/+; Rosa26tdTomato/+?mouse.

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Fig. 3 Cre-mediated recombination in the brain of Cx3cr1Cre/+; Rosa26tdTomato/+?mouse. TdTomato(red) expression can be detected in the microglial cells of Cx3cr1Cre/+; Rosa26tdTomato/+?mouse.

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Fig. 4 Detection of tdTomato(red) in various tissues of Cx3cr1Cre/+; Rosa26tdTomato/+?mice. Cre mediated recombination can be detected in some cells of the brain, liver, lung, stomach, salivary gland, small intestine, spinal cord, spleen, testis and epididymis, skin and subcutaneous tissue, skeletal muscle and thymus. Tdtomato expression can not be observed in the brown fat, heart, retina, kidney or pancreas. (For more detailed information please contact our technical advisor.)



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