Tert-CreERT2-2A-EGFP

品系全名

C57BL/6Smoc-Tertem1(CreERT2-2A-GFP-WPRE-PA)Smoc

目錄號

NM-KI-18037

品系狀態(tài)

精子凍存

導出PDF

基因信息

基因名
Tert

品系描述

在Tert基因起始密碼子位點定點敲入CreERT2-2A-GFP-WPRE-PA表達框。
應用領域:Cre工具鼠

驗證數(shù)據(jù)

image.png

Fig1. CreERT2 mediated recombination in small intestine of TertCreERT2-EGFP/+;Rosa26tdTomato/+ mouse.

image.png

Fig2. Detection of EGFP(green) and tdTomato(red) in various tissues of TertCreERT2-EGFP/+;Rosa26tdTomato/+ mouse. Expression tissues include: small intestine, lung, liver, salivary gland, kidney, pancreas. A few cells expressed in brain, stomach, colon, spleen, skin, thymus, ovary. Tissues that unexpressed include eye, heart, brown fat. No significant EGFP positive signal was detected. (6.5-months old, female) (For more detailed information please contact our technical advisor.)?



你也可能感興趣

Tamoxifen誘導Cre-ERT2小鼠 使用指南

Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質(zhì)內(nèi)處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產(chǎn)物4-OHT(雌激素類似物)與ERT結合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。

查看
【小鼠大學問】基因工程小鼠的命名規(guī)則

常見的基因工程小鼠可以分為兩種命名方式,包括基因定點修飾的小鼠命名,比如:敲除、敲入、點突變等等,和隨機轉基因的小鼠命名。

查看