Fabp7-CreERT2
品系全名
C57BL/6Smoc-Fabp7em2(Kozak-CreERT2-WPRE-pA)Smoc
目錄號
NM-KI-231749
品系狀態(tài) 精子凍存
基因信息
基因名
Fabp7
品系描述
驗證數據
Fig1. CreERT2 mediated recombination in dorsal root ganglia of Fabp7Cre/+; Rosa26tdTomato/+ mouse.?
Fig2. Detection of tdTomato(red) in various tissues of AicdaCre/+; Rosa26tdTomato/+.?
Tissues expressing tdTomato: brain, spinal cord, eyes, stomach, salivary glands, pituitary, kidneys, pancreas, large intestine, small intestine, spleen, skin, thymus, dorsal root ganglia. Tissues with low expression: lungs, liver, brown fat, adrenal glands, reproductive organs. Tissues without expression: heart, muscles. (51-days old, female) (For more detailed information please contact our technical advisor.)?
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Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質內處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產物4-OHT(雌激素類似物)與ERT結合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。
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