Dhh-Cre

品系全名

C57BL/6Smoc-Dhhem(Kozak-Cre-WPRE-pA)1Smoc

目錄號

NM-KI-225049

品系狀態(tài)

精子凍存

導(dǎo)出PDF

基因信息

基因名
Dhh

基因曾用名

C78960

NCBI ID

MGI ID

Ensembl ID

Pubmed

人類同源基因

DHH

品系描述

將Kozak-Cre-WPRE-pA插入到小鼠Dhh基因起始密碼子處。

驗證數(shù)據(jù)

image.png

Fig1. Cre mediated recombination in testis of DhhCre/+;Rosa26tdTomato/+ mouse.?

image.png

Fig2. Cre mediated recombination in sciatic nerve of DhhCre/+;Rosa26tdTomato/+ mouse.

image.png

Fig3. Detection of tdTomato(red) in various tissues of DhhCre/+;Rosa26tdTomato/+ mouse. The tissues of double-positive mice were cryosectioned and directly examined, revealing expression in the following organs: brain, heart, lung, liver, stomach, salivary gland, thymus, sciatic nerve, kidney, pancreas, small intestine, colon, spleen and ovary, skin, adrenal gland and pituitary gland; sporadic cell expression tissues: spinal cord, retina, brown fat, muscle. A few cells expressing it were also identified in the spinal cord, retina, brown fat, and muscle. (4-weeks old, male) (For more detailed information please contact our technical advisor.)?

你也可能感興趣

Tamoxifen誘導(dǎo)Cre-ERT2小鼠 使用指南

Cre-ERT2在無Tamoxifen誘導(dǎo)的情況下，在細胞質(zhì)內(nèi)處于無活性狀態(tài)；當(dāng)Tamoxifen誘導(dǎo)后，Tamoxifen的代謝產(chǎn)物4-OHT（雌激素類似物）與ERT結(jié)合，可使Cre-ERT2進核發(fā)揮Cre重組酶活性。

查看
【小鼠大學(xué)問】基因工程小鼠的命名規(guī)則

常見的基因工程小鼠可以分為兩種命名方式，包括基因定點修飾的小鼠命名，比如：敲除、敲入、點突變等等，和隨機轉(zhuǎn)基因的小鼠命名。

查看