Qrfp-Cre
品系全名
C57BL/6Smoc-Qrfpem(iCre-pA)Smoc
目錄號
NM-KI-204994
品系狀態(tài) 精子凍存
基因信息
基因名
Qrfp
品系描述
驗證數(shù)據(jù)
Fig 1. Cre-mediated recombination in testis of QrfpCre/+; Rosa26tdTomato/+ mice.
Fig 2. Cre-mediated recombination in brain of QrfpCre/+; Rosa26tdTomato/+ mice.
Fig 3. Detection of tdTomato (red) in various tissues of QrfpCre/+; Rosa26tdTomato/+ mice. Expression tissues include: brain, lung, salivary glands, kidney, testis and epididymis, skin, thymus. A few cells expressed in adrenal gland. Tissues that unexpressed include pituitary gland, retina, heart, liver, stomach, brown fat, spinal cord, pancreas, large and small intestine, spleen, muscle. (3-week old, male) (For more detailed information please contact our technical advisor.)?
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Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質內處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產物4-OHT(雌激素類似物)與ERT結合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。
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