hTL1A(BALB/c)

品系全名

BALB/cAnSmoc-Tnfsf15em1(hTNFSF15)Smoc

目錄號(hào)

NM-HU-220602

品系狀態(tài)

胚胎凍存

導(dǎo)出PDF

基因信息

基因名
Tnfsf15

基因曾用名

Tl1; Tl1a; Vegi; Tnlg1b

NCBI ID

MGI ID

Ensembl ID

Pubmed

人類同源基因

TNFSF15

品系描述

利用同源重組，將小鼠Tnfsf15 基因進(jìn)行人源化修飾。

驗(yàn)證數(shù)據(jù)

image.png

Fig.1 Detection of TL1A expression in bladder by RT-PCR.?

Wild type: only one band at 285 bp with primers F1/R1 (mTl1a);

Homozygous: only one band at 233 bp with primers F2/R2 (hTL1A).


Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hTL1A (A) and mTL1A (B) expression in lung homogenate by ELISA (n=3).?

Abbr. HO, homozygous;WT, wild type.

Note. hTL1A and BALB/c mice were i.p. injected with LPS for 6h. The anti-human and mouse TL1A kit cross-reacted with mTL1A and humanized TL1A.

image.png

Fig.3 Detection of TL1A expression on endothelial and epithelial cells in lung in hTL1A mice

Note. The hom hTL1A mice were stimulated with LPS in vivo.?

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