MC38-hIL1β

導出PDF

品系基本信息

驗證數(shù)據(jù)

2.png

Fig1.?The anti-hIL1β mAb Canakinumab alone or in combination with Tecentriq significantly inhibited the growth of MC38-hIL1β tumors in C57mice, demonstrating that this model is suitable for evaluating the in vivo efficacy of anti-hIL1β mAb alone and in combination with PD-1/PD-L1 antibodies.?


4.png

Fig. 2 Blinatumomab injections were repeated daily for 5 days and immune cells in the PB of mice after therapy were measured by flow cytometry.


你也可能感興趣

Tamoxifen誘導Cre-ERT2小鼠 使用指南

Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質內處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產物4-OHT(雌激素類似物)與ERT結合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。

查看
【小鼠大學問】基因工程小鼠的命名規(guī)則

常見的基因工程小鼠可以分為兩種命名方式,包括基因定點修飾的小鼠命名,比如:敲除、敲入、點突變等等,和隨機轉基因的小鼠命名。

查看