Col1a1-IRES-EGFP-IRES-MerCreMer

品系全名

C57BL/6Smoc-Col1a1em1(IRES-EGFP-IRES-MerCreMer)Smoc

目錄號

NM-KI-240492

品系狀態(tài)

活體

導(dǎo)出PDF

基因信息

基因名
Col1a1

基因曾用名

Cola1; Mov13; Cola-1; Mov-13; Col1a-1

染色體位置

11

NCBI ID

MGI ID

Ensembl ID

Pubmed

人類同源基因

COL1A1

品系描述

將IRES-EGFP-IRES-MerCreMer插入到小鼠Col1a1基因終止密碼子處。該品系繁育無法獲得純合子，建議使用雜合子進行研究。

鑒定方案

驗證數(shù)據(jù)

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Fig1. Cre mediated recombination in femur of Col1a1MerCreMer/+;Rosa26tdTomato/+ mouse.?

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Fig2. Cre mediated recombination in skull of Col1a1MerCreMer/+;Rosa26tdTomato/+?mouse.?

image.png


Fig3. Detection of EGFP(green) and tdTomato(red) in various tissues of Col1a1MerCreMer/+;Rosa26tdTomato/+ mouse. The tissues expressing both tdTomato and EGFP include: bone, skull, teeth, eye, lung, stomach, salivary gland, brown adipose tissue, adrenal gland, kidney, small intestine, large intestine, epididymis, and thymus.

The tissues expressing tdTomato include: brain, spinal cord, heart, pancreas, spleen, muscle, skin, and pituitary gland.

In the control group, tdTomato shows minimal leaky expression in: eye, adrenal gland, bone, teeth, epididymis, skin, and thymus.(83-days old, male) (For more detailed information please contact our technical advisor.)?



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