Tek-Cre(SD)
品系全名
SD-Tekem1(Cre)Smoc
目錄號
NR-KI-210133
品系狀態(tài) 活體
基因信息
基因名
Tek
品系描述
驗證數(shù)據(jù)
Fig 1. Cre-mediated recombination in aorta of TekCre/+; Rosa26mTmG+?rat.
Fig 2. Detection of tdTomato (red) and GFP (green) in various tissues of TekCre/+; Rosa26mTmG+?rat.?Expression tissues include: brain, eyeball, heart, lung, liver, salivary gland, brown fat, pituitary gland, aorta, kidney, spleen, pancreas, testis, skin, adrenal gland. A few cells expressed in spinal cord, stomach, colon, small intestine, muscle, thymus. (37-day old, male) (For more detailed information please contact our technical advisor.)?
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Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質(zhì)內(nèi)處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產(chǎn)物4-OHT(雌激素類似物)與ERT結(jié)合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。
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