可用于構(gòu)建移植瘤模型的原代細(xì)胞系：
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藥效評價案例
Fig. Growth of KPC mouse tumour cells inoculated into the liver, lung and pancreas of wild C57BL/6 mice.
Fig. Evaluation of antitumour efficacy of cell lines derived from tumour masses in KPC mice (host mouse pairs are C57BL/6 mice). a. Efficacy tumourigenic curve, b. Efficacy body weight curve, c, photographs of tumours.
Fig. Stk11/EGFP/Kras-LSL-G12D primary lung cancer mouse model can trigger lung cancer by AAV-CRE induction.
Fig. Evaluation of anti-tumour efficacy of Stk11/EGFP/Kras-LSL-G12D tumour mass-derived cell line.
藥效評價案例
Fig. Homograft experiments of spontaneous hepatocellular carcinoma tumour blocks in H11-LSL-Myc/Rosa26-LSL-LuC-EGFP/Ab-Cre triple-positive mice. a. Tumour growth, b. Efficacy tumourigenicity curves, and c. Changes in efficacy body weight.
