2210010C04Rik-D23A

品系全名

C57BL/6Smoc-2210010C04Rikem1D23ASmoc

目錄號

NM-KI-232248

品系狀態(tài)

精子凍存

導(dǎo)出PDF

基因信息

基因名

基因曾用名

-

NCBI ID

MGI ID

Ensembl ID

Pubmed

品系描述

該小鼠攜帶2210010C04Rik-D23A突變。

驗證數(shù)據(jù)

image.png

Fig 1. The pancreas of a heterozygous female mouse with RikD23A/+ mutation.?

Pancreatic tissue from 2-week-old and 23-week-old RikD23A/+ heterozygous female mice exhibited a loss of acinar cells, accompanied by infiltration of inflammatory cells, acinar-ductal metaplasia, fat infiltration, and fibrotic changes.The scale bar corresponds to 200 μm.


image.png

Pathology scores:0 represents within the normal range, 1 represents mild, 2 represents moderate, and 3 represents marked

圖片1.png

Fig 2.?The pancreas of a heterozygous male mouse with RikD23A/+ mutation

Pancreatic tissue from 4-week-old and 8-week-old RikD23A/+ heterozygous male mice exhibited a loss of acinar cells, accompanied by infiltration of inflammatory cells, acinar-ductal metaplasia, fat infiltration, and fibrotic changes；The degree of fat infiltration and fibrosis is not significant in 2-week-old mice, and other phenotypes are mild.The scale bar corresponds to 200 μm.

image.png

Pathology scores:0 represents within the normal range, 1 represents mild, 2 represents moderate, and 3 represents marked


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