hPVRL2
品系全名
C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
目錄號
NM-HU-2000084
品系狀態(tài) 胚胎凍存
基因信息
基因名
Nectin2
品系描述
通過同源重組，將小鼠Nectin2基因進行人源化修飾。
應(yīng)用領(lǐng)域：免疫治療；藥物篩選
*使用本品系發(fā)表的文獻需注明: hPVRL2 mice (Cat. NO. NM-HU-2000084) were purchased from Shanghai Model Organisms Center, Inc..
驗證數(shù)據(jù)
Fig1. Detection of PVRL2 expression in duodenum and large Intestine by RT-PCR.?
Wild type: only one band at 342 bp with primers F1/R1 (mPvrl2);
Homozygous: only one band at 228 bp with primers F2/R2 (hPVRL2);
Abbr. M, DNA marker; HO, homozygous;? WT, wild type.
Fig2. Detection of human PVRL2 expression in duodenum and large Intestine?in hPVRL2 KI mice.?
Fig3. Detection of hPVRL2 expression on marcophages and dendritic cells in hPVRL2 KI mice.
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