hIL18BP

品系全名

C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc

目錄號

NM-HU-210039

品系狀態(tài)

胚胎凍存

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基因信息

基因名
Il18bp

基因曾用名

MC54L; Igifbp; IL-18BP

NCBI ID

MGI ID

Ensembl ID

Pubmed

人類同源基因

IL18BP

品系描述

通過同源重組，將小鼠Il18bp基因進行人源化修飾。
應用領域：免疫治療；藥物篩選

驗證數據

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Fig1. Detection of IL18BP expression in thymus and liver by RT-PCR.?Wild type: only one band at 354 bp with primers F1/R1(mIl18bp);Heterozygous: one band at 354 bp with primers F1/R1(mIl18bp) and one band at 220 bp with primers F2/R2(hIL18BP); Abbr.. M, DNA marker;?HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Detection of IL18BP expression in thymus and liver by RT-PCR.? Wild type: only one band at 354 bp with primers F1/R1(mIl18bp); Homozygous: only one band at 220 bp with primers F2/R2(hIL18BP);? Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig3. Detection of hIL18BP expression in serum by ELISA.?Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig4. Detection of mIL18BP expression in serum by ELISA.?Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig5.?Detection of hIL18BP expression in serum by ELISA (n=3).?Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig6.?Detection of mIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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