hCD19/hCD3EDG(BALB/c)

品系全名

BALB/cAnSmoc-Cd19em(hCD19)Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Smoc

目錄號

NM-XA-240066

品系狀態(tài)

胚胎凍存

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品系描述

通過hCD3EDG(BALB/c)(NM-HU-220122)與hCD19(BALB/c)(NM-HU-220606)小鼠交配獲得。

驗證數(shù)據(jù)

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Fig.1 Detection of immune phenotype in WT BALB/c and HO/HO hCD3EDG/hCD19 mice.(male, n=3)

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Fig.2 Detection of phenotype in Peripheral blood in WT BALB/c and HO/HO hCD3EDG/hCD19 mice.

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Fig.3 Detection of phenotype in Spleen in WT BALB/c and HO/HO hCD3EDG/hCD19 mice.

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Fig.4 Detection of phenotype in Lymph node in WT BALB/c and HO/HO hCD3EDG/hCD19 mice.

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Fig.5 Blinatumomab injections were repeated daily for 5 days and immune cells in the PB of mice after therapy were measured by flow cytometry(n=6). Average?± SEM;*P<0.05,**P<0.01,***P<0.001;(Student' s t test)

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