hCD7(V2)

品系全名

C57BL/6Smoc-Cd7em2(hCD7)Smoc

目錄號(hào)

NM-HU-232423

品系狀態(tài)

胚胎凍存

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基因信息

基因名
Cd7

品系描述

利用同源重組,將小鼠Cd7基因進(jìn)行人源化修飾。

驗(yàn)證數(shù)據(jù)

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Fig.1 Detection of CD7 expression in duodenum and small intestine by RT-PCR.?

Wild type: only one band at 107 bp with primers F1/R1 (mCd7);

Homozygous: only one band at 163 bp with primers F2/R2 (hCD7).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig.2 Detection of m/h CD7 expression on T cells in Blood (A), spleen (B) and thymus (C) in hCD7(2) KI mice.

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Fig.3 Detection of hCD7 expression on T cells in Blood (A), spleen (B) and thymus (C) in hCD7(2) KI mice.

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Fig.4 Detection of m/h CD7 expression on NKs in Blood (A) and spleen (B) in hCD7(2) KI mice.

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Fig.5 Analysis of leukocytes cell subpopulation in Spleen (A) and thymus (B) in WT and HO hCD7(2) mice.


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