靶點人源化小鼠是敲入小鼠的一種，通常會將鼠源基因的部分或全部替換為人類同源基因。
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品系名：C57BL/6Smoc-Cd3etm(hCD3E)Cd3dtm(hCD3D)Cd3gtm(hCD3G)Folh1tm(hFOLH1B) /Smoc
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品系名：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Sirpatm2(hSIRPA)Cd47em1(hCD47)Smoc
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品系名：BALB/cAnSmoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tgtn(hTNFRSF10C)1Smoc
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品系名：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tpbgem1(hTPBG) /Smoc
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品系名：BALB/cAnSmoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tnfrsf23em1(2A-TNFRSF10C-WPRE-pA)Smoc
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