Pbsn-2A-CreERT2

品系全名

C57BL/6Smoc-Pbsnem1(V5-2A-CreERT2-WPRE-polyA)Smoc

目錄號

NM-KI-200190

品系狀態(tài)

活體

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基因信息

基因名
Pbsn

基因曾用名

PB; Prbs

NCBI ID

MGI ID

Ensembl ID

Pubmed

人類同源基因

PBSN

品系描述

將V5-2A-CreERT2-WPRE-polyA共表達結(jié)構(gòu)插入到小鼠Pbsn基因終止密碼子處。
應用領域：Cre工具鼠，前列腺上皮細胞

驗證數(shù)據(jù)

pbsn.png

Fig1. Expression Pattern of Tomato in?PbsnCreERT2/+;Rosa26tdTomato/+?mice.

CreERT2-mediated recombination in prostate epithelial cells of?PbsnCreERT2/+?;?Rosa26tdTomato/+?mice. This strain represents an effective tool for generating prostate specific-targeted mutants.

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Fig2. Cre mediated recombination in prostate of PbsnCreERT2/+;Rosa26tdTomato/+?mouse.?

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Fig3. Detection of tdTomato(red) in various tissues of PbsnCreERT2/+;Rosa26tdTomato/+?mouse.?Expression tissues include: prostate, salivary gland. A few cells expressed in adrenal gland, pancreas, testis, muscle and thymus. Tissues that unexpressed include brain, spinal cord, eyeball, heart, lung, liver, stomach, brown fat, kidney, colon, small intestine, spleen, and skin. (9-week old, male) (For more detailed information please contact our technical advisor.)

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