Csf1r-IRES-Cre

品系全名

C57BL/6Smoc-Csf1rem3(IRES-iCre)Smoc

目錄號

NM-KI-190026

品系狀態(tài)

活體

導(dǎo)出PDF

基因信息

基因名
CSF1R

基因曾用名

Fms; Fim2; CD115; Csfmr; Fim-2; CSF-1R; M-CSFR; M-CSF-R; AI323359

NCBI ID

MGI ID

Ensembl ID

Pubmed

人類同源基因

CSF1R

品系描述

將IRES-iCre共表達結(jié)構(gòu)插入到小鼠Csf1r基因終止密碼子處。
應(yīng)用領(lǐng)域：Cre工具鼠

驗證數(shù)據(jù)

csf1r.png

Fig1. Flow assay of fluorescent gene expression in peripheral blood macrophages of Csf1r-Cre+/-;R26-mTmG+/- mice. In cre-expressing F4/80 macrophages, tdTomato was excised and the cells were labelled with EGFP; in F4/80 macrophages without cre expression, the cells were labelled with tdtomato and EGFP was not expressed.

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Fig2. Cre mediated recombination in skin of Csf1r Cre/+;Rosa26 tdTomato/+ mice.

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Fig3. Detection of tdTomato(red) in various tissues of Csf1r?Cre/+;Rosa26?tdTomato/+ mice. The tissues that express tdTomato include: brain, eyeball, heart, lungs, liver, salivary glands, kidneys, small intestine, large intestine, ovaries, skin, adrenal gland, gallbladder. A small amount of expressiontdTomato are spinal cord. (7.5-weeks old, female) (For more detailed information please contact our technical advisor.)?

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