Adora2a-CreERT2
品系全名
C57BL/6Smoc-Adora2aem1(Kozak-CreERT2-WPRE-pA)Smoc
目錄號
NM-KI-241092
品系狀態(tài) 精子凍存
基因信息
基因名
Adora2a
品系描述
鑒定方案
驗證數(shù)據(jù)
Fig 1. CreERT2-mediated recombination in brain of Adora2aCreERT2/+; Rosa26tdTomato/+ mice.
Fig 2. Detection of tdTomato (red) in various tissues of Adora2aCreERT2/+; Rosa26tdTomato/+ mice. Tissue distribution of tdTomato expression: brain, eye, lung, liver, salivary gland, thymus, bone marrow, kidney, pancreas, small intestine, spleen, reproductive system, mesenteric lymph nodes. (45-days old, female) (For more detailed information please contact our technical advisor.)?
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Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質(zhì)內(nèi)處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產(chǎn)物4-OHT(雌激素類似物)與ERT結(jié)合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。
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