Cd8a-2A-CreERT2

品系全名

C57BL/6Smoc-Cd8aem1(2A-CreERT2)Smoc

目錄號(hào)

NM-KI-234690

品系狀態(tài)

活體

導(dǎo)出PDF

基因信息

基因名
Cd8a

品系描述

將2A-CreERT2插入到小鼠Cd8a基因終止密碼子處。

鑒定方案


驗(yàn)證數(shù)據(jù)

image.png

Fig1. CreERT2 mediated recombination in thymus of Cd8aCreERT2/+; Rosa26tdTomato/+mouse.?

image.png

Fig2. Detection of tdTomato(red) in various tissues of Cd8aCreERT2/+; Rosa26tdTomato/+ mouse. Expression tissues include: lungs, liver, stomach, large intestine, small intestine, spleen, adrenal glands, reproductive organs, muscles, thymus. Scattered cells were expressed in adrenal gland, spleen, muscle. Tissues that unexpressed include brain, spinal cord, eyes, heart, salivary glands, brown adipose tissue, kidneys, pancreas, skin, pituitary gland. (59-days old, male) (For more detailed information please contact our technical advisor.)?


你也可能感興趣

Tamoxifen誘導(dǎo)Cre-ERT2小鼠 使用指南

Cre-ERT2在無(wú)Tamoxifen誘導(dǎo)的情況下,在細(xì)胞質(zhì)內(nèi)處于無(wú)活性狀態(tài);當(dāng)Tamoxifen誘導(dǎo)后,Tamoxifen的代謝產(chǎn)物4-OHT(雌激素類似物)與ERT結(jié)合,可使Cre-ERT2進(jìn)核發(fā)揮Cre重組酶活性。

查看
【小鼠大學(xué)問(wèn)】基因工程小鼠的命名規(guī)則

常見的基因工程小鼠可以分為兩種命名方式,包括基因定點(diǎn)修飾的小鼠命名,比如:敲除、敲入、點(diǎn)突變等等,和隨機(jī)轉(zhuǎn)基因的小鼠命名。

查看