Hdc-2A-CreERT2

品系全名

C57BL/6Smoc-Hdcem(2A-CreERT2)Smoc

目錄號

NM-KI-220044

品系狀態(tài)

精子凍存

導出PDF

基因信息

基因名
Hdc

品系描述

將2A-CreERT2插入到小鼠Hdc基因終止密碼子處。

驗證數(shù)據(jù)

image.png

Fig1. CreERT2 mediated recombination in brain of HdcCreERT2/+; Rosa26tdTomato/+ mouse.?

image.png

Fig2. Detection of tdTomato(red) in various tissues of HdcCreERT2/+; Rosa26tdTomato/+ mouse.?

The tissues that express tdTomato include: brain, spinal cord, lungs, liver, stomach, adrenal glands, kidneys, spleen, reproductive organs, thymus, and pituitary gland. Tissues with minimal tdTomato expression include: small intestine and skin.?

Tissues that do not express tdTomato: heart, eyes, salivary glands, brown adipose tissue, pancreas, large intestine, and muscle.?

In the control group, tdTomato shows very minimal leaky expression in the brain, stomach, adrenal glands, kidneys, spleen, and thymus. (8-weeks old, male) (For more detailed information please contact our technical advisor.)?



你也可能感興趣

Tamoxifen誘導Cre-ERT2小鼠 使用指南

Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質內處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產(chǎn)物4-OHT(雌激素類似物)與ERT結合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。

查看
【小鼠大學問】基因工程小鼠的命名規(guī)則

常見的基因工程小鼠可以分為兩種命名方式,包括基因定點修飾的小鼠命名,比如:敲除、敲入、點突變等等,和隨機轉基因的小鼠命名。

查看