Mrc1-2A-CreERT2
品系全名
C57BL/6Smoc-Mrc1em2(2A-CreERT2)Smoc
目錄號
NM-KI-220031
品系狀態(tài) 活體
基因信息
基因名
Mrc1
品系描述
驗證數(shù)據(jù)
Fig 1. Cre-mediated recombination in liver of Mrc1CreERT2/+; Rosa26tdTomato/+ mice.
Fig 2. Detection of tdTomato (red) in various tissues of Mrc1CreERT2/+; Rosa26tdTomato/+?mice.?Expression tissues include: liver. A few cells expressed in large intestine, spleen, skin, thymus. Tissues that unexpressed include brain, spinal cord, retina, heart, lung, stomach, salivary glands, brown fat, pituitary gland, kidney, pancreas, small intestine, testis, muscle, adrenal gland. (4.5-month old, male) (For more detailed information please contact our technical advisor.)?
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Cre-ERT2在無Tamoxifen誘導的情況下,在細胞質內處于無活性狀態(tài);當Tamoxifen誘導后,Tamoxifen的代謝產物4-OHT(雌激素類似物)與ERT結合,可使Cre-ERT2進核發(fā)揮Cre重組酶活性。
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