Foxp3-IRES-DTRGFP

品系全名

C57BL/6Smoc-Foxp3em3(IRES-DTREGFP)Smoc

目錄號

NM-KI-190046

品系狀態(tài)

活體

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基因信息

基因名
Foxp3

品系描述

將IRES-DTREGFP共表達結(jié)構(gòu)插入到小鼠Foxp3基因終止密碼子處。
應(yīng)用領(lǐng)域:DTR工具鼠

驗證數(shù)據(jù)

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Fig1. Expression of GFP on Tregs in Blood and Spleen in Foxp3-IRES-DTRGFP KI mice.?

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Fig2. Percentages of Tregs in the peripheral blood and spleen of Foxp3-IRES-DTRGFP KI mice treated with diphtheria toxin (DT).

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Fig3. The percent of? Treg+ and other immune cells in peripheral blood of MC38 tumor-bearing? Foxp3-IRES-DTRGFP mice is detected by FACS.?(In collaboration with CrownBio)?

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Fig4. The percent of? Treg+ and other immune cells in spleen and tumor of MC38 tumor-bearing? Foxp3-IRES-DTRGFP mice is detected by FACS.?(In collaboration with CrownBio)?

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Fig5.? The growth of MC38 tumors in Foxp3-IRES-DTRGFP mice and C57BL/6 mice.?(In collaboration with CrownBio)?



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