hIL1RL1

品系全名

C57BL/6Smoc-Il1rl1tm4(hIL1RL1)/Smoc

目錄號(hào)

NM-HU-2000067

品系狀態(tài)

精子凍存

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基因信息

基因名
Il1rl1

基因曾用名

T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1

NCBI ID

MGI ID

Ensembl ID

Pubmed

人類同源基因

IL1RL1

品系描述

通過(guò)同源重組，將小鼠Il1rl1基因進(jìn)行人源化修飾。
應(yīng)用領(lǐng)域：細(xì)胞因子人源化模型；藥物篩選

驗(yàn)證數(shù)據(jù)

image.png

Fig1. Detection of IL1RL1 expression in large intestine by RT-PCR in?hIL1RL1 mice.?

Wild type: only one band at 296 bp with primers F1/R1(mIl1rl1);

Homoygous: only one band at 367 bp with primers F2/R2(hIL1RL1);

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2.?Expression of hIL1RL1 on CD4+ T cells in spleen?in hIL1RL1/hIL4/hIL4R mice (NM-HU-232112), which were generated by crossing hIL4/hIL4R (NM-HU-2000106) with hIL1RL1 (NM-HU-2000067).

image.png

Fig3. Expression of hIL1RL1 on mast cells in bone marrow?in hIL1RL1/hIL4/hIL4R mice (NM-HU-232112), which were generated by crossing hIL4/hIL4R (NM-HU-2000106) with hIL1RL1 (NM-HU-2000067).


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