CT26-hTROP2

導(dǎo)出PDF

品系基本信息

細(xì)胞系名稱

CT26-hTROP2

目錄號

NM-S24A-TM38

品系描述

TROP2基因人源化的CT26結(jié)腸癌細(xì)胞系

品系狀態(tài)

成瘤性驗(yàn)證完成

驗(yàn)證數(shù)據(jù)

image.png

Fig.1 hTROP2 expression on in vitro cultured cells of CT26-hTROP2.

image.png

Fig.2?In vivo validation of CT26-hTROP2 in BALB/c mice.BALB/c mice were inoculated with CT26-hTROP2 subcutaneously at 3×106 cells/mouse inoculum for tumor development. The day of vaccination for mice is defined as Day 0, and tumor measurement and weight measurement begin on the 7th day after vaccination, twice a week.

image.png

Fig.3?hTROP2 expression in tumors after in vivo growth of CT26-hTROP2 in wild type BALB/c mice.When the MTV reaches 500-800 mm3, take one tube from each group and send it to FACS for testing (Markers: L/D, mCD45, hTROP2). A，the MTV reaches 800 mm3. B，the MTV reaches 1500 mm3.

你也可能感興趣

Tamoxifen誘導(dǎo)Cre-ERT2小鼠 使用指南

Cre-ERT2在無Tamoxifen誘導(dǎo)的情況下，在細(xì)胞質(zhì)內(nèi)處于無活性狀態(tài)；當(dāng)Tamoxifen誘導(dǎo)后，Tamoxifen的代謝產(chǎn)物4-OHT（雌激素類似物）與ERT結(jié)合，可使Cre-ERT2進(jìn)核發(fā)揮Cre重組酶活性。

查看
【小鼠大學(xué)問】基因工程小鼠的命名規(guī)則

常見的基因工程小鼠可以分為兩種命名方式，包括基因定點(diǎn)修飾的小鼠命名，比如：敲除、敲入、點(diǎn)突變等等，和隨機(jī)轉(zhuǎn)基因的小鼠命名。

查看