4T1-hCD47

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品系基本信息

細(xì)胞系名稱

4T1-hCD47

目錄號(hào)

NM-S07-TM02

品系描述

CD47基因人源化的4T1細(xì)胞系

品系狀態(tài)

成瘤性驗(yàn)證完成

驗(yàn)證數(shù)據(jù)

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Fig1. hCD47 expression on in vitro cultured cells of 4T1-hCD47. (In collaboration with CrownBio)

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Fig2. In vivo validation of 4T1-hCD47 in hSIRPA/hCD47 (BALB/c) mice. (In collaboration with CrownBio) hSIRPA/hCD47 Balb/C mice were inoculated subcutaneously with 4T1 at 3×105 and 4T1-hCD47 at 3×106 cells/mouse inoculum for tumor development.

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Fig3. hCD47 expression in tumors after in vivo growth of 4T1-hCD47 in hSIRPA/hCD47(BALB/c) mice. (In collaboration with CrownBio) The tumors were collected at day 35 and day 40 post tumor cell inoculation.

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