腫瘤靶點人源化小鼠是將腫瘤靶點基因進行人源化修飾而產(chǎn)生的小鼠。該類模型正常組織內(nèi)也含有人源腫瘤靶點基因，因此可以用于評價靶向人源腫瘤藥物的毒性及安全性。
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hPLAG1-IRES-Luciferase-2A-tdTomato-wpre-polyA)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST-IRES-tdTomato-WPRE-polyA)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST4-IRES-EGFP-WPRE-polyA)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Krasem4(LSL-G12D)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem(SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-WNT1-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
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品系名：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Smoc
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